7S0Q

Head region of a complex of IGF-I with the ectodomain of a hybrid insulin receptor / type 1 insulin-like growth factor receptor

7S0Q の概要

• エントリーDOI: 10.2210/pdb7s0q/pdb
• EMDBエントリー: 24791
• 分子名称: Insulin-like growth factor 1 receptor, Insulin receptor, Insulin-like growth factor I, ... (7 entities in total)
• 機能のキーワード: insulin receptor, type 1 insulin like growth factor receptor, hybrid receptor, insulin like growth factor i, leucine zipper, cryo electron microscopy, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 229736.71

構造登録者

Xu, Y.,Lawrence, M.C. (登録日: 2021-08-30, 公開日: 2022-07-06, 最終更新日: 2022-08-17)

• 主引用文献: Xu, Y.,Margetts, M.B.,Venugopal, H.,Menting, J.G.,Kirk, N.S.,Croll, T.I.,Delaine, C.,Forbes, B.E.,Lawrence, M.C.; How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor.; Structure, 30:1098-1108.e6, 2022; PubMed: 35660159; DOI: 10.1016/j.str.2022.05.007

実験手法

ELECTRON MICROSCOPY (3.7 Å)