7S0I

CRYSTAL STRUCTURE OF N1 NEURAMINIDASE FROM A/Michigan/45/2015(H1N1)

7S0I の概要

• エントリーDOI: 10.2210/pdb7s0i/pdb
• 分子名称: Neuraminidase, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: influenza a virus, h1n1, neuraminidase, head domain, measles virus phosphoprotein tetramerization domain, hydrolase
• 由来する生物種: Influenza A virus (A/Michigan/45/2015(H1N1))
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 44354.46

構造登録者

Zhu, X.,Wilson, I.A. (登録日: 2021-08-30, 公開日: 2021-12-08, 最終更新日: 2023-10-18)

• 主引用文献: Strohmeier, S.,Amanat, F.,Zhu, X.,McMahon, M.,Deming, M.E.,Pasetti, M.F.,Neuzil, K.M.,Wilson, I.A.,Krammer, F.; A Novel Recombinant Influenza Virus Neuraminidase Vaccine Candidate Stabilized by a Measles Virus Phosphoprotein Tetramerization Domain Provides Robust Protection from Virus Challenge in the Mouse Model.; Mbio, 12:e0224121-e0224121, 2021; PubMed: 34809451; DOI: 10.1128/mBio.02241-21

実験手法

X-RAY DIFFRACTION (2.892 Å)