7RZ4

Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK 200775

7RZ4 の概要

• エントリーDOI: 10.2210/pdb7rz4/pdb
• EMDBエントリー: 24750
• 分子名称: Glutamate receptor 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: ampa receptor, ion channel, neurotransmission, synapse, tarp gamma-5, membrane protein
• 由来する生物種: Rattus norvegicus (Rat)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 485484.75

構造登録者

Gangwar, S.P.,Klykov, O.V.,Yelshanskaya, M.V.,Sobolevsky, A.I. (登録日: 2021-08-27, 公開日: 2021-10-27, 最終更新日: 2022-02-16)

• 主引用文献: Klykov, O.,Gangwar, S.P.,Yelshanskaya, M.V.,Yen, L.,Sobolevsky, A.I.; Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.; Mol.Cell, 81:4771-4783.e7, 2021; PubMed: 34678168; DOI: 10.1016/j.molcel.2021.09.030

実験手法

ELECTRON MICROSCOPY (3.6 Å)