7RV9
Crystal structure of the BCL6 BTB domain in complex with OICR-10269
Summary for 7RV9
Entry DOI | 10.2210/pdb7rv9/pdb |
Related | 7LWE 7LWF 7LWG |
Descriptor | Isoform 2 of B-cell lymphoma 6 protein, N-[5-chloro-2-(4-methylpiperazin-1-yl)pyridin-4-yl]-2-{5-(3-cyano-4-hydroxy-5-methylphenyl)-3-[3-(1-methyl-1H-pyrazol-4-yl)prop-2-yn-1-yl]-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl}acetamide, DIMETHYL SULFOXIDE, ... (4 entities in total) |
Functional Keywords | immunity, inflammatory response, transcription repressor, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 15289.07 |
Authors | Kuntz, D.A.,Prive, G.G. (deposition date: 2021-08-18, release date: 2022-08-24, Last modification date: 2023-10-18) |
Primary citation | Watson, I.,Isaac, M. Structure of the BCL6 BTB domain To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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