7RTH
Crystal structure of an anti-lysozyme nanobody in complex with an anti-nanobody Fab "NabFab"
Summary for 7RTH
Entry DOI | 10.2210/pdb7rth/pdb |
Descriptor | Fragment Antigen-Binding Light Chain, Fragment Antigen-Binding Heavy Chain, Nanobody, ... (8 entities in total) |
Functional Keywords | antigen, fab, single-domain antibody, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 27 |
Total formula weight | 574950.14 |
Authors | Filippova, E.V.,Mukherjee, S.,Bloch, J.S.,Locher, K.P.,Kossiakoff, A.A. (deposition date: 2021-08-13, release date: 2021-09-01, Last modification date: 2023-10-18) |
Primary citation | Bloch, J.S.,Mukherjee, S.,Kowal, J.,Filippova, E.V.,Niederer, M.,Pardon, E.,Steyaert, J.,Kossiakoff, A.A.,Locher, K.P. Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 34782475DOI: 10.1073/pnas.2115435118 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.19 Å) |
Structure validation
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