7RTH

Crystal structure of an anti-lysozyme nanobody in complex with an anti-nanobody Fab "NabFab"

Summary for 7RTH

• Entry DOI: 10.2210/pdb7rth/pdb
• Descriptor: Fragment Antigen-Binding Light Chain, Fragment Antigen-Binding Heavy Chain, Nanobody, ... (8 entities in total)
• Functional Keywords: antigen, fab, single-domain antibody, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 27
• Total formula weight: 574950.14

Authors

Filippova, E.V.,Mukherjee, S.,Bloch, J.S.,Locher, K.P.,Kossiakoff, A.A. (deposition date: 2021-08-13, release date: 2021-09-01, Last modification date: 2023-10-18)

• Primary citation: Bloch, J.S.,Mukherjee, S.,Kowal, J.,Filippova, E.V.,Niederer, M.,Pardon, E.,Steyaert, J.,Kossiakoff, A.A.,Locher, K.P.; Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 34782475; DOI: 10.1073/pnas.2115435118

Experimental method

X-RAY DIFFRACTION (3.19 Å)