7RTB

Peptide-19 bound to the Glucagon-Like Peptide-1 Receptor (GLP-1R)

7RTB の概要

• エントリーDOI: 10.2210/pdb7rtb/pdb
• EMDBエントリー: 24680
• 分子名称: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• 機能のキーワード: glucagon-like peptide-1 receptor (glp-1r), peptide-19 cryo-em, membrane protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 163991.76

構造登録者

Johnson, R.M.,Danev, R.,Sexton, P.M.,Wootten, D. (登録日: 2021-08-12, 公開日: 2021-10-06)

• 主引用文献: Johnson, R.M.,Zhang, X.,Piper, S.J.,Nettleton, T.J.,Vandekolk, T.H.,Langmead, C.J.,Danev, R.,Sexton, P.M.,Wootten, D.; Cryo-EM structure of the dual incretin receptor agonist, peptide-19, in complex with the glucagon-like peptide-1 receptor.; Biochem.Biophys.Res.Commun., 578:84-90, 2021; PubMed: 34547628; DOI: 10.1016/j.bbrc.2021.09.016

実験手法

ELECTRON MICROSCOPY (2.14 Å)