7RSM
Crystal structure of pyrrolysyl-tRNA synthetase (N346D/C348S/Y384F) in complex with o-Chlorophenylalanine and AMP-PNP
Summary for 7RSM
Entry DOI | 10.2210/pdb7rsm/pdb |
Descriptor | Pyrrolysine--tRNA ligase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 2-chloro-L-phenylalanine, ... (4 entities in total) |
Functional Keywords | trna synthetase, pylrs, o-chlorophenylalanine, rna binding protein |
Biological source | Methanosarcina mazei (Methanosarcina frisia) |
Total number of polymer chains | 4 |
Total formula weight | 126236.76 |
Authors | |
Primary citation | Vatansever, E.C.,Yang, K.S.,Geng, Z.Z.,Qiao, Y.,Li, P.,Xu, S.,Liu, W.R. A Designed, Highly Efficient Pyrrolysyl-tRNA Synthetase Mutant Binds o-Chlorophenylalanine Using Two Halogen Bonds. J.Mol.Biol., 434:167534-167534, 2022 Cited by PubMed: 35278475DOI: 10.1016/j.jmb.2022.167534 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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