7RQW

Cryo-EM structure of the full-length TRPV1 with RTx at 4 degrees Celsius, in an open state, class III

Summary for 7RQW

• Entry DOI: 10.2210/pdb7rqw/pdb
• EMDB information: 24638
• Descriptor: Transient receptor potential cation channel subfamily V member 1, resiniferatoxin, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (5 entities in total)
• Functional Keywords: ligand-gating ion channel, membrane protein
• Biological source: Rattus norvegicus (Rat)
• Total number of polymer chains: 4
• Total formula weight: 409326.62

Authors

Kwon, D.H.,Suo, Y.,Lee, S.-Y. (deposition date: 2021-08-08, release date: 2022-06-01)

• Primary citation: Kwon, D.H.,Zhang, F.,Fedor, J.G.,Suo, Y.,Lee, S.Y.; Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis.; Nat Commun, 13:2874-2874, 2022; PubMed: 35610228; DOI: 10.1038/s41467-022-30602-2

Experimental method

ELECTRON MICROSCOPY (3.11 Å)