7RQR
Structure of chimeric antibody L9heavy_F10light with PfCSP peptide NANPNVDP
Summary for 7RQR
Entry DOI | 10.2210/pdb7rqr/pdb |
Related | 7RQP |
Descriptor | L9 Heavy Chain, F10 Kappa Chain, PfCSP peptide NANPNVDP, ... (5 entities in total) |
Functional Keywords | malaria, antibody, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 6 |
Total formula weight | 97604.68 |
Authors | Hurlburt, N.K.,Pancera, M. (deposition date: 2021-08-06, release date: 2022-03-02, Last modification date: 2023-10-18) |
Primary citation | Wang, L.T.,Hurlburt, N.K.,Schon, A.,Flynn, B.J.,Flores-Garcia, Y.,Pereira, L.S.,Kiyuka, P.K.,Dillon, M.,Bonilla, B.,Zavala, F.,Idris, A.H.,Francica, J.R.,Pancera, M.,Seder, R.A. The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria. Cell Rep, 38:110367-110367, 2022 Cited by PubMed: 35172158DOI: 10.1016/j.celrep.2022.110367 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.23 Å) |
Structure validation
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