7RNQ

Holo structure of engineered TrpB, 2B9-H275E, from Pyrococcus furiosus in the extended-open conformation

7RNQ の概要

• エントリーDOI: 10.2210/pdb7rnq/pdb
• 分子名称: Tryptophan synthase beta chain 1, PHOSPHATE ION, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: plp, tryptophan synthase, directed evolution, biosynthetic protein
• 由来する生物種: Pyrococcus furiosus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 174910.60

構造登録者

Higgins, P.M.,Buller, A.R. (登録日: 2021-07-29, 公開日: 2022-08-03, 最終更新日: 2023-11-15)

• 主引用文献: McDonald, A.D.,Higgins, P.M.,Buller, A.R.; Substrate multiplexed protein engineering facilitates promiscuous biocatalytic synthesis.; Nat Commun, 13:5242-5242, 2022; PubMed: 36068220; DOI: 10.1038/s41467-022-32789-w

実験手法

X-RAY DIFFRACTION (2.102 Å)