7RK2
Crystal structure of the human astrovirus serotype 8 capsid spike in complex with scFv 2D9, an astrovirus-neutralizing antibody, at 2.65-A resolution
Summary for 7RK2
Entry DOI | 10.2210/pdb7rk2/pdb |
Descriptor | Capsid protein VP25, scFv 2D9 (3 entities in total) |
Functional Keywords | viral protein, capsid protein, icosahedral virus, single chain variable fragment |
Biological source | Human astrovirus-8 (HAstV-8) More |
Total number of polymer chains | 4 |
Total formula weight | 104957.46 |
Authors | Meyer, L.,Cuellar, C.,DuBois, R.M. (deposition date: 2021-07-21, release date: 2021-10-13, Last modification date: 2023-10-18) |
Primary citation | Ricemeyer, L.,Aguilar-Hernandez, N.,Lopez, T.,Espinosa, R.,Lanning, S.,Mukherjee, S.,Cuellar, C.,Lopez, S.,Arias, C.F.,DuBois, R.M. Structures of Two Human Astrovirus Capsid/Neutralizing Antibody Complexes Reveal Distinct Epitopes and Inhibition of Virus Attachment to Cells. J.Virol., 96:e0141521-e0141521, 2022 Cited by PubMed: 34613806DOI: 10.1128/JVI.01415-21 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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