7RK2

Crystal structure of the human astrovirus serotype 8 capsid spike in complex with scFv 2D9, an astrovirus-neutralizing antibody, at 2.65-A resolution

7RK2 の概要

• エントリーDOI: 10.2210/pdb7rk2/pdb
• 分子名称: Capsid protein VP25, scFv 2D9 (3 entities in total)
• 機能のキーワード: viral protein, capsid protein, icosahedral virus, single chain variable fragment
• 由来する生物種: Human astrovirus-8 (HAstV-8); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 104957.46

構造登録者

Meyer, L.,Cuellar, C.,DuBois, R.M. (登録日: 2021-07-21, 公開日: 2021-10-13, 最終更新日: 2023-10-18)

• 主引用文献: Ricemeyer, L.,Aguilar-Hernandez, N.,Lopez, T.,Espinosa, R.,Lanning, S.,Mukherjee, S.,Cuellar, C.,Lopez, S.,Arias, C.F.,DuBois, R.M.; Structures of Two Human Astrovirus Capsid/Neutralizing Antibody Complexes Reveal Distinct Epitopes and Inhibition of Virus Attachment to Cells.; J.Virol., 96:e0141521-e0141521, 2022; PubMed: 34613806; DOI: 10.1128/JVI.01415-21

実験手法