7RJO

Crystal structure of human Bromodomain containing protein 4 (BRD4) in complex with hnRNPK

7RJO の概要

• エントリーDOI: 10.2210/pdb7rjo/pdb
• 分子名称: Bromodomain-containing protein 4, Heterogeneous nuclear ribonucleoprotein K, SODIUM ION, ... (6 entities in total)
• 機能のキーワード: brd4, hnrnpk, acetyllysine, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 16522.96

構造登録者

Fedorov, E.,Islam, K.,Ghosh, A. (登録日: 2021-07-21, 公開日: 2022-08-03, 最終更新日: 2024-10-16)

• 主引用文献: Wagner, S.,Fedorov, E.,Sudhamalla, B.,Jnawali, H.N.,Debiec, R.,Ghosh, A.,Islam, K.; Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization; Biorxiv, 2021; DOI: 10.1101/2021.07.28.453719

実験手法

X-RAY DIFFRACTION (1.38 Å)