7RJL

Crystal structure of human Bromodomain containing protein 3 (BRD3) in complex with SHMT

Summary for 7RJL

Entry DOI	10.2210/pdb7rjl/pdb
Descriptor	Bromodomain-containing protein 3, Serine hydroxymethyltransferase, cytosolic, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	brd3, shmt, acetyllysine, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	31280.10
Authors	Fedorov, E.,Islam, K.,Ghosh, A. (deposition date: 2021-07-21, release date: 2022-08-03, Last modification date: 2024-11-13)
Primary citation	Wagner, S.,Fedorov, E.,Sudhamalla, B.,Jnawali, H.N.,Debiec, R.,Ghosh, A.,Islam, K. Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization Biorxiv, 2021 Cited by DOI: 10.1101/2021.07.28.453719 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation