7RIA

Griffithsin variant Y28A/Y68A/Y110A

Summary for 7RIA

Entry DOI	10.2210/pdb7ria/pdb
Descriptor	Griffithsin, alpha-D-mannopyranose, SULFATE ION, ... (4 entities in total)
Functional Keywords	lectin, mannose binding protein, hiv inhibitor, c3 pseudosymmetry, carbohydrate binding sites, sugar binding protein
Biological source	Griffithsia sp. (strain Q66D336) (Red alga)
Total number of polymer chains	2
Total formula weight	30356.68
Authors	Zhao, G.,Sun, J.,Bewley, C.A. (deposition date: 2021-07-19, release date: 2022-05-18, Last modification date: 2023-10-25)
Primary citation	Sun, J.,Zhao, G.,Bylund, T.,Lee, M.,Adibhatla, S.,Kwong, P.D.,Chuang, G.Y.,Rawi, R.,Bewley, C.A. C 3 -Symmetric Aromatic Core of Griffithsin Is Essential for Potent Anti-HIV Activity. Acs Chem.Biol., 17:1450-1459, 2022 Cited by PubMed: 35537058 DOI: 10.1021/acschembio.1c00990 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation