7RHZ
Heterodimer of Cre recombinase mutants D33A/A36V/R192A and R72E/L115D/R119D in complex with loxP DNA.
Summary for 7RHZ
Entry DOI | 10.2210/pdb7rhz/pdb |
EMDB information | 24472 |
Descriptor | Recombinase cre, DNA (44-MER), ... (4 entities in total) |
Functional Keywords | cre, recombinase, dimer, loxp, recombination-dna complex, recombination/dna |
Biological source | Escherichia phage P1 (Bacteriophage P1) More |
Total number of polymer chains | 4 |
Total formula weight | 104114.44 |
Authors | Stachowski, K.,Foster, M.P. (deposition date: 2021-07-19, release date: 2022-01-19, Last modification date: 2024-06-05) |
Primary citation | Stachowski, K.,Norris, A.S.,Potter, D.,Wysocki, V.H.,Foster, M.P. Mechanisms of Cre recombinase synaptic complex assembly and activation illuminated by Cryo-EM. Nucleic Acids Res., 50:1753-1769, 2022 Cited by PubMed: 35104890DOI: 10.1093/nar/gkac032 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.48 Å) |
Structure validation
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