7RHM
Structure of Q67H/N74D mutant of disulfide stabilized HIV-1 CA hexamer
Summary for 7RHM
Entry DOI | 10.2210/pdb7rhm/pdb |
Related | 7RAO 7RAR |
Descriptor | CAPSID PROTEIN P24, IODIDE ION, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | inhibitor, viral protein, viral protein-inhibitor complex, viral protein/inhibitor |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 1 |
Total formula weight | 26157.16 |
Authors | Bester, S.M.,Kvaratskhelia, M. (deposition date: 2021-07-17, release date: 2022-07-27, Last modification date: 2023-10-18) |
Primary citation | Bester, S.M.,Adu-Ampratwum, D.,Annamalai, A.S.,Wei, G.,Briganti, L.,Murphy, B.C.,Haney, R.,Fuchs, J.R.,Kvaratskhelia, M. Structural and Mechanistic Bases of Viral Resistance to HIV-1 Capsid Inhibitor Lenacapavir. Mbio, 13:e0180422-e0180422, 2022 Cited by PubMed: 36190128DOI: 10.1128/mbio.01804-22 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.16 Å) |
Structure validation
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