7RAJ
Structure of PfCSP peptide 21 with antibody iGL-CIS43.D3
Summary for 7RAJ
Entry DOI | 10.2210/pdb7raj/pdb |
Descriptor | iGL-CIS43.D3 Fab Heavy chain, iGL-CIS43.D3 Fab light chain, ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP-PRO-ASN-ALA-ASN, ... (6 entities in total) |
Functional Keywords | antibody, plasmodium falciparum, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 50381.77 |
Authors | Tripathi, P.,Kwong, P.D. (deposition date: 2021-07-01, release date: 2021-12-15, Last modification date: 2024-10-16) |
Primary citation | Kratochvil, S.,Shen, C.H.,Lin, Y.C.,Xu, K.,Nair, U.,Da Silva Pereira, L.,Tripathi, P.,Arnold, J.,Chuang, G.Y.,Melzi, E.,Schon, A.,Zhang, B.,Dillon, M.,Bonilla, B.,Flynn, B.J.,Kirsch, K.H.,Kisalu, N.K.,Kiyuka, P.K.,Liu, T.,Ou, L.,Pancera, M.,Rawi, R.,Reveiz, M.,Seignon, K.,Wang, L.T.,Waring, M.T.,Warner, J.,Yang, Y.,Francica, J.R.,Idris, A.H.,Seder, R.A.,Kwong, P.D.,Batista, F.D. Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies. Immunity, 54:2859-2876.e7, 2021 Cited by PubMed: 34788599DOI: 10.1016/j.immuni.2021.10.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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