7R8Y

Ancestral protein AncThEn of Phosphomethylpyrimidine kinases family

7R8Y の概要

• エントリーDOI: 10.2210/pdb7r8y/pdb
• 分子名称: Phosphomethylpyrimidine Kinase, 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE (2 entities in total)
• 機能のキーワード: ancestral protein reconstruction, 5-phosphohydroxymethyl-2-methylpyrimidine kinase, phosphomethylpyrimidine kinases family, enzyme evolution, transferase
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 60952.37

構造登録者

Munoz, S.,Maturana, P.,Gonzalez-Ordenes, F.,Cea, P.,Castro-Fernandez, V. (登録日: 2021-06-27, 公開日: 2022-06-29, 最終更新日: 2024-08-21)

• 主引用文献: Cea, P.A.,Perez, M.,Herrera, S.M.,Munoz, S.M.,Fuentes-Ugarte, N.,Coche-Miranda, J.,Maturana, P.,Guixe, V.,Castro-Fernandez, V.; Deciphering Structural Traits for Thermal and Kinetic Stability across Protein Family Evolution through Ancestral Sequence Reconstruction; Mol.Biol.Evol., 41:-, 2024; DOI: 10.1093/molbev/msae127

実験手法

X-RAY DIFFRACTION (3.2 Å)