7R79
Histoplasma capsulatum H88 Calcium Binding Protein 1 (Cbp1)
Summary for 7R79
| Entry DOI | 10.2210/pdb7r79/pdb |
| Descriptor | Calcium-binding protein (2 entities in total) |
| Functional Keywords | histoplasma, h88, fungal pathogenesis, secreted effector, macrophage lysis, cbp1, toxin |
| Biological source | Ajellomyces capsulatus (Darling's disease fungus, Histoplasma capsulatum) |
| Total number of polymer chains | 4 |
| Total formula weight | 31615.35 |
| Authors | Herrera, N.,Azimova, D.,Sil, A.,Rosenberg, O.S. (deposition date: 2021-06-24, release date: 2022-04-13, Last modification date: 2024-04-03) |
| Primary citation | Azimova, D.,Herrera, N.,Duvenage, L.,Voorhies, M.,Rodriguez, R.A.,English, B.C.,Hoving, J.C.,Rosenberg, O.,Sil, A. Cbp1, a fungal virulence factor under positive selection, forms an effector complex that drives macrophage lysis. Plos Pathog., 18:e1010417-e1010417, 2022 Cited by PubMed: 35731824DOI: 10.1371/journal.ppat.1010417 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
Download full validation report
