7R4O

Structure of human hydroxyacid oxidase 1 bound with 2-((4H-1,2,4-triazol-3-yl)thio)-1-(4-(3-chlorophenyl)piperazin-1-yl)ethan-1-one

7R4O の概要

• エントリーDOI: 10.2210/pdb7r4o/pdb
• 関連するPDBエントリー: 5qib 5qic 5qid 5qie 5qif 5qig 5qih 7r4n
• 分子名称: Hydroxyacid oxidase 1, 2-((4H-1,2,4-triazol-3-yl)thio)-1-(4-(3-chlorophenyl)piperazin-1-yl)ethan-1-one, FLAVIN MONONUCLEOTIDE, ... (4 entities in total)
• 機能のキーワード: hao1, hydroxyacid oxidase, glycolate oxidase, fragment screening, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40946.43

構造登録者

Mackinnon, S.,Bezerra, G.A.,Krojer, T.,Bradley, A.R.,Talon, R.,Brandeo-Neto, J.,Douangamath, A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Oppermann, U.,Brennan, P.E.,Yue, W.W. (登録日: 2022-02-08, 公開日: 2022-05-04, 最終更新日: 2024-01-31)

• 主引用文献: Mackinnon, S.,Bezerra, G.A.,Krojer, T.,Bradley, A.R.,Talon, R.,Brandeo-Neto, J.,Douangamath, A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Oppermann, U.,Brennan, P.E.,Yue, W.W.; Structure of human hydroxyacid oxidase 1 bound with 5-bromo-N-methyl-1H-indazole-3-carboxamide; To Be Published,

実験手法

X-RAY DIFFRACTION (1.5 Å)