7QZR

Structure of native leukocyte myeloperoxidase in complex with the Staphyloccal Peroxidase Inhibitor SPIN from Staphylococcus aureus

7QZR の概要

• エントリーDOI: 10.2210/pdb7qzr/pdb
• 分子名称: Myeloperoxidase light chain, CALCIUM ION, PHOSPHATE ION, ... (13 entities in total)
• 機能のキーワード: phagocytosis innate immune response inhibitor complex, oxidoreductase
• 由来する生物種: Staphylococcus aureus; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 160750.10

構造登録者

Pfanzagl, V.,Brito, J.A. (登録日: 2022-01-31, 公開日: 2022-10-26, 最終更新日: 2024-01-31)

• 主引用文献: Leitgeb, U.,Furtmuller, P.G.,Hofbauer, S.,Brito, J.A.,Obinger, C.,Pfanzagl, V.; The staphylococcal inhibitory protein SPIN binds to human myeloperoxidase with picomolar affinity but only dampens halide oxidation.; J.Biol.Chem., 298:102514-102514, 2022; PubMed: 36150500; DOI: 10.1016/j.jbc.2022.102514

実験手法

X-RAY DIFFRACTION (2.18 Å)