7QUO

FimH lectin domain in complex with oligomannose-6

7QUO の概要

• エントリーDOI: 10.2210/pdb7quo/pdb
• 関連するPDBエントリー: 7BHD
• 分子名称: FimH, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NICKEL (II) ION, ... (5 entities in total)
• 機能のキーワード: type-1 fimbriae, escherichia coli, fimh, adhesin, lectin, oligomannose, high-mannose, cell adhesion
• 由来する生物種: Escherichia coli BL21(DE3)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 70888.70

構造登録者

Bouckaert, J.,Bourenkov, G.P. (登録日: 2022-01-18, 公開日: 2023-02-01, 最終更新日: 2024-02-14)

• 主引用文献: Krammer, E.M.,Bridot, C.,Serna, S.,Echeverria, B.,Semwal, S.,Roubinet, B.,van Noort, K.,Wilbers, R.H.,Bourenkov, G.,de Ruyck, J.,Landemarre, L.,Reichardt, N.,Bouckaert, J.; Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci- and high-mannose type N-glycan receptors; J.Biol.Chem., 299:104627-, 2023; DOI: 10.1016/j.jbc.2023.104627

実験手法

X-RAY DIFFRACTION (3 Å)