7QNR

SMYD3 in complex with fragment FL01791

Summary for 7QNR

Entry DOI	10.2210/pdb7qnr/pdb
Related	7QLB 7QNU
Descriptor	Histone-lysine N-methyltransferase SMYD3, S-ADENOSYLMETHIONINE, ZINC ION, ... (5 entities in total)
Functional Keywords	methyltransferase, epigenetic, oncogen, histone, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	50198.28
Authors	Lund, B.A.,Cederfelt, D.,Dobritzsch, D. (deposition date: 2021-12-22, release date: 2023-04-05, Last modification date: 2024-04-24)
Primary citation	FitzGerald, E.A.,Cederfelt, D.,Lund, B.A.,Myers, N.,Zhang, H.,Dobritzsch, D.,Danielson, H. Identification of fragments targeting SMYD3 using highly sensitive kinetic and multiplexed biosensor-based screening Rsc Med Chem, 2024 Cited by DOI: 10.1039/D4MD00093E PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.57 Å)

Structure validation