7QKR

Cryo-EM structure of ABC transporter STE6-2p from Pichia pastoris with Verapamil at 3.2 A resolution

Summary for 7QKR

Entry DOI	10.2210/pdb7qkr/pdb
EMDB information	14049
Descriptor	Plasma membrane ATP-binding cassette transporter required for the export of a-factor, Dexverapamil, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
Functional Keywords	abc transporter, abcb, mdr, membrane protein, pichia pastoris, transport protein
Biological source	Komagataella phaffii CBS 7435
Total number of polymer chains	1
Total formula weight	146504.17
Authors	Schleker, E.S.M.,Reinhart, C. (deposition date: 2021-12-18, release date: 2022-10-26, Last modification date: 2024-07-17)
Primary citation	Schleker, E.S.M.,Buschmann, S.,Xie, H.,Welsch, S.,Michel, H.,Reinhart, C. Structural and functional investigation of ABC transporter STE6-2p from Pichia pastoris reveals unexpected interaction with sterol molecules. Proc.Natl.Acad.Sci.USA, 119:e2202822119-e2202822119, 2022 Cited by PubMed: 36256814 DOI: 10.1073/pnas.2202822119 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation