7QKR

Cryo-EM structure of ABC transporter STE6-2p from Pichia pastoris with Verapamil at 3.2 A resolution

7QKR の概要

• エントリーDOI: 10.2210/pdb7qkr/pdb
• EMDBエントリー: 14049
• 分子名称: Plasma membrane ATP-binding cassette transporter required for the export of a-factor, Dexverapamil, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
• 機能のキーワード: abc transporter, abcb, mdr, membrane protein, pichia pastoris, transport protein
• 由来する生物種: Komagataella phaffii CBS 7435
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 146504.17

構造登録者

Schleker, E.S.M.,Reinhart, C. (登録日: 2021-12-18, 公開日: 2022-10-26, 最終更新日: 2024-07-17)

• 主引用文献: Schleker, E.S.M.,Buschmann, S.,Xie, H.,Welsch, S.,Michel, H.,Reinhart, C.; Structural and functional investigation of ABC transporter STE6-2p from Pichia pastoris reveals unexpected interaction with sterol molecules.; Proc.Natl.Acad.Sci.USA, 119:e2202822119-e2202822119, 2022; PubMed: 36256814; DOI: 10.1073/pnas.2202822119

実験手法

ELECTRON MICROSCOPY (3.2 Å)