7QK9
Crystal structure of the ALDH1A3-ATP complex
Summary for 7QK9
Entry DOI | 10.2210/pdb7qk9/pdb |
Descriptor | Aldehyde dehydrogenase family 1 member A3, ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... (7 entities in total) |
Functional Keywords | aldh1a3, aldehyde dehydrogenase family 1 member a3, atp, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 110087.33 |
Authors | Castellvi, A.,Farres, J. (deposition date: 2021-12-17, release date: 2022-04-20, Last modification date: 2024-01-31) |
Primary citation | Castellvi, A.,Pequerul, R.,Barracco, V.,Juanhuix, J.,Pares, X.,Farres, J. Structural and biochemical evidence that ATP inhibits the cancer biomarker human aldehyde dehydrogenase 1A3. Commun Biol, 5:354-354, 2022 Cited by PubMed: 35418200DOI: 10.1038/s42003-022-03311-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.782 Å) |
Structure validation
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