7QDP

Crystal structure of FLT3 T343I in complex with the canonical ligand FL

Summary for 7QDP

• Entry DOI: 10.2210/pdb7qdp/pdb
• Descriptor: Fms-related tyrosine kinase 3 ligand, Receptor-type tyrosine-protein kinase FLT3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: activation complex, complex, receptor tyrosine kinase, rtk-iii, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 334224.54

Authors

Pannecoucke, E.,Savvides, S.N. (deposition date: 2021-11-27, release date: 2022-12-14, Last modification date: 2024-01-31)

• Primary citation: Pannecoucke, E.,Savvides, S.N.; Crystal structure of FLT3 T343I in complex with the canonical ligand FL; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.691 Å)