7QC1

Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline-tRNA ligase) from Plasmodium falciparum in complex with MAT436

7QC1 の概要

• エントリーDOI: 10.2210/pdb7qc1/pdb
• 分子名称: Proline--tRNA ligase, [(2~{R},3~{S})-2-[3-(7-bromanyl-6-chloranyl-4-oxidanylidene-quinazolin-3-yl)-2-oxidanylidene-propyl]piperidin-3-yl] ~{N}-[4-[[3-(2,3-dihydro-1~{H}-inden-2-ylcarbamoyl)pyrazin-2-yl]carbamoyl]piperazin-1-yl]sulfonylcarbamate, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: proline, aminoacyl-trna synthetase, ligase, protein biosynthesis
• 由来する生物種: Plasmodium falciparum (isolate 3D7)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 178859.97

構造登録者

Johansson, C.,Tye, M.,Payne, N.C.,Mazitschek, R.,Oppermann, U.C.T. (登録日: 2021-11-22, 公開日: 2021-12-08, 最終更新日: 2024-01-31)

• 主引用文献: Johansson, C.,Tye, M.,Payne, N.C.,Mazitschek, R.,Oppermann, U.C.T.; Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline-tRNA ligase) from Plasmodium falciparum in complex with MAT436; To Be Published,

実験手法

X-RAY DIFFRACTION (2.51 Å)