7QA4

Crystal structure of stabilized H3N2 A/Hong Kong/1/1968 Hemagglutinin at 2.2 Angstrom

7QA4 の概要

• エントリーDOI: 10.2210/pdb7qa4/pdb
• 分子名称: Hemagglutinin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: influenza, hemagglutinin, stabilized, fusion protein, unknown function, viral protein
• 由来する生物種: Influenza A virus (strain A/Hong Kong/1/1968 H3N2)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 59761.06

構造登録者

Milder, F.J.,Langedijk, J.P.M. (登録日: 2021-11-16, 公開日: 2022-02-02, 最終更新日: 2022-03-30)

• 主引用文献: Milder, F.J.,Jongeneelen, M.,Ritschel, T.,Bouchier, P.,Bisschop, I.J.M.,de Man, M.,Veldman, D.,Le, L.,Kaufmann, B.,Bakkers, M.J.G.,Juraszek, J.,Brandenburg, B.,Langedijk, J.P.M.; Universal stabilization of the influenza hemagglutinin by structure-based redesign of the pH switch regions.; Proc.Natl.Acad.Sci.USA, 119:-, 2022; PubMed: 35131851; DOI: 10.1073/pnas.2115379119

実験手法

X-RAY DIFFRACTION (2.19 Å)