7Q3J

Computationally designed thioredoxin subjected to stability optimizing mutations.

7Q3J の概要

• エントリーDOI: 10.2210/pdb7q3j/pdb
• 関連するPDBエントリー: 5j7d
• 分子名称: MM9, GLYCEROL (3 entities in total)
• 機能のキーワード: de-novo protein design, deep mutational scanning, stability, screening, de novo protein
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 26939.01

構造登録者

Norrild, R.K.,Johansson, K.E.,O'Shea, C.,Lindorff-Larsen, K.,Winther, J.R.,Morth, J.P. (登録日: 2021-10-27, 公開日: 2022-11-16, 最終更新日: 2024-02-07)

• 主引用文献: Norrild, R.K.,Johansson, K.E.,O'Shea, C.,Morth, J.P.,Lindorff-Larsen, K.,Winther, J.R.; Increasing protein stability by inferring substitution effects from high-throughput experiments.; Cell Rep Methods, 2:100333-100333, 2022; PubMed: 36452862; DOI: 10.1016/j.crmeth.2022.100333

実験手法

X-RAY DIFFRACTION (1.9 Å)