7Q2I
Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with Tetrahydrofurfurylamine
Summary for 7Q2I
Entry DOI | 10.2210/pdb7q2i/pdb |
Descriptor | Cholinephosphate cytidylyltransferase, 1-[(2R)-oxolan-2-yl]methanamine, Guanidinium, ... (4 entities in total) |
Functional Keywords | plasmodium falciparum cct inhibitors fragments, transferase |
Biological source | Plasmodium falciparum |
Total number of polymer chains | 1 |
Total formula weight | 21072.50 |
Authors | Duclovel, C.,Gelin, M.,Krimm, I.,Cerdan, R.,Guichou, J.-F. (deposition date: 2021-10-25, release date: 2022-11-09, Last modification date: 2024-01-31) |
Primary citation | Duclovel, C.,Gelin, M.,Wein, S.,Wengelnik, K.,Krimm, I.,Guichou, J.F.,Cerdan, R. Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.87 Å) |
Structure validation
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