7Q2E
mycolic acid methyltransferase Hma (MmaA4) from Mycobac-terium tuberculosis in complex with ZT424
Summary for 7Q2E
| Entry DOI | 10.2210/pdb7q2e/pdb |
| Related | 7Q2B 7Q2C 7Q2D 7Q2F 7Q2G 7Q2H |
| Descriptor | Hydroxymycolate synthase MmaA4, 2-bromanylpyridin-3-ol, DIMETHYL SULFOXIDE, ... (4 entities in total) |
| Functional Keywords | mycolic acid methyltransferase mycobacterium tuberculosis fragment based ligand discovery, transferase |
| Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
| Total number of polymer chains | 1 |
| Total formula weight | 36929.70 |
| Authors | Maveyraud, L.,Galy, R.,Mourey, L. (deposition date: 2021-10-25, release date: 2022-02-02, Last modification date: 2024-01-31) |
| Primary citation | Galy, R.,Ballereau, S.,Genisson, Y.,Mourey, L.,Plaquevent, J.C.,Maveyraud, L. Fragment-Based Ligand Discovery Applied to the Mycolic Acid Methyltransferase Hma (MmaA4) from Mycobacterium tuberculosis : A Crystallographic and Molecular Modelling Study. Pharmaceuticals, 14:-, 2021 Cited by PubMed: 34959681DOI: 10.3390/ph14121282 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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