7Q0Z

Crystal structure of CTX-M-14

Summary for 7Q0Z

• Entry DOI: 10.2210/pdb7q0z/pdb
• Related: 7Q0Y
• Descriptor: Beta-lactamase, GLYCEROL, SULFATE ION, ... (4 entities in total)
• Functional Keywords: lactamase, antibiotic, resistence, hydrolase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 1
• Total formula weight: 28644.97

Authors

Werner, N.,Perbandt, M.,Hinrichs, W.,Prester, A.,Rohde, H.,Aepfelbacher, M.,Betzel, C. (deposition date: 2021-10-17, release date: 2022-04-13, Last modification date: 2024-01-31)

• Primary citation: Perbandt, M.,Werner, N.,Prester, A.,Rohde, H.,Aepfelbacher, M.,Hinrichs, W.,Betzel, C.; Structural basis to repurpose boron-based proteasome inhibitors Bortezomib and Ixazomib as beta-lactamase inhibitors.; Sci Rep, 12:5510-5510, 2022; PubMed: 35365689; DOI: 10.1038/s41598-022-09392-6

Experimental method

X-RAY DIFFRACTION (1 Å)