7Q0Q

Acetyltrasferase(3) type IIIa in complex with 3-N-methyl-nemycin B

Summary for 7Q0Q

• Entry DOI: 10.2210/pdb7q0q/pdb
• Descriptor: Aminoglycoside N(3)-acetyltransferase III, GLYCEROL, ACETATE ION, ... (7 entities in total)
• Functional Keywords: acetyltrasferase, aminoglycosides, inhibitor, complex, antibiotic
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 2
• Total formula weight: 59943.27

Authors

Pontillo, N.,Guskov, A. (deposition date: 2021-10-16, release date: 2022-11-02, Last modification date: 2024-01-31)

• Primary citation: Pontillo, N.,Warszawik, E.M.,Partipilo, M.,Stetsenko, A.,Loznik, M.,Yang, X.,Slotboom, D.J.,Guskov, A.,Herrmann, A.; The 3-N-alkylation of the neomycin B outmaneuvers the aminoglycoside resistant enzyme acetyltransferase(3)IIIa via an unexpected mechanism; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.96 Å)