7PXX
The crystal structure of Leishmania major Pteridine Reductase 1 in complex with substrate folic acid
Summary for 7PXX
| Entry DOI | 10.2210/pdb7pxx/pdb |
| Descriptor | Pteridine reductase 1, FOLIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (8 entities in total) |
| Functional Keywords | enzyme-substrate complex, rossmann fold, cofactor, oxidoreductase |
| Biological source | Leishmania major More |
| Total number of polymer chains | 4 |
| Total formula weight | 127348.43 |
| Authors | Di Pisa, F.,Dello Iacono, L.,Mangani, S. (deposition date: 2021-10-08, release date: 2022-04-06, Last modification date: 2024-01-31) |
| Primary citation | Dello Iacono, L.,Di Pisa, F.,Mangani, S. Crystal structure of the ternary complex of Leishmania major pteridine reductase 1 with the cofactor NADP + /NADPH and the substrate folic acid. Acta Crystallogr.,Sect.F, 78:170-176, 2022 Cited by PubMed: 35400669DOI: 10.1107/S2053230X22002795 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
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