7PXX

The crystal structure of Leishmania major Pteridine Reductase 1 in complex with substrate folic acid

7PXX の概要

• エントリーDOI: 10.2210/pdb7pxx/pdb
• 分子名称: Pteridine reductase 1, FOLIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (8 entities in total)
• 機能のキーワード: enzyme-substrate complex, rossmann fold, cofactor, oxidoreductase
• 由来する生物種: Leishmania major; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 127348.43

構造登録者

Di Pisa, F.,Dello Iacono, L.,Mangani, S. (登録日: 2021-10-08, 公開日: 2022-04-06, 最終更新日: 2024-01-31)

• 主引用文献: Dello Iacono, L.,Di Pisa, F.,Mangani, S.; Crystal structure of the ternary complex of Leishmania major pteridine reductase 1 with the cofactor NADP + /NADPH and the substrate folic acid.; Acta Crystallogr.,Sect.F, 78:170-176, 2022; PubMed: 35400669; DOI: 10.1107/S2053230X22002795

実験手法

X-RAY DIFFRACTION (1.81 Å)