7PSU
Structure of protein kinase CK2alpha mutant K198R associated with the Okur-Chung Neurodevelopmental Syndrome
Summary for 7PSU
| Entry DOI | 10.2210/pdb7psu/pdb |
| Descriptor | Casein kinase II subunit alpha, 1,2-ETHANEDIOL, SULFATE ION, ... (5 entities in total) |
| Functional Keywords | protein kinase ck2, casein kinase 2, csnk2a1 mutant k198r, okur-chung neurodevelopmental syndrome, transferase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 96309.94 |
| Authors | Werner, C.,Gast, A.,Lindenblatt, D.,Nickelsen, K.,Niefind, K.,Jose, J.,Hochscherf, J. (deposition date: 2021-09-23, release date: 2022-03-23, Last modification date: 2024-01-31) |
| Primary citation | Werner, C.,Gast, A.,Lindenblatt, D.,Nickelsen, A.,Niefind, K.,Jose, J.,Hochscherf, J. Structural and Enzymological Evidence for an Altered Substrate Specificity in Okur-Chung Neurodevelopmental Syndrome Mutant CK2 alpha Lys198Arg. Front Mol Biosci, 9:831693-831693, 2022 Cited by PubMed: 35445078DOI: 10.3389/fmolb.2022.831693 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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