7PSU

Structure of protein kinase CK2alpha mutant K198R associated with the Okur-Chung Neurodevelopmental Syndrome

7PSU の概要

• エントリーDOI: 10.2210/pdb7psu/pdb
• 分子名称: Casein kinase II subunit alpha, 1,2-ETHANEDIOL, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: protein kinase ck2, casein kinase 2, csnk2a1 mutant k198r, okur-chung neurodevelopmental syndrome, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 96309.94

構造登録者

Werner, C.,Gast, A.,Lindenblatt, D.,Nickelsen, K.,Niefind, K.,Jose, J.,Hochscherf, J. (登録日: 2021-09-23, 公開日: 2022-03-23, 最終更新日: 2024-01-31)

• 主引用文献: Werner, C.,Gast, A.,Lindenblatt, D.,Nickelsen, A.,Niefind, K.,Jose, J.,Hochscherf, J.; Structural and Enzymological Evidence for an Altered Substrate Specificity in Okur-Chung Neurodevelopmental Syndrome Mutant CK2 alpha Lys198Arg.; Front Mol Biosci, 9:831693-831693, 2022; PubMed: 35445078; DOI: 10.3389/fmolb.2022.831693

実験手法

X-RAY DIFFRACTION (1.77 Å)