7PSH

Crystal structure of beta-glucuronidase from Acidobacterium capsulatum at 1.24 Angstrom resolution

Summary for 7PSH

Entry DOI	10.2210/pdb7psh/pdb
Descriptor	Beta-glucuronidase (2 entities in total)
Functional Keywords	glycoside hydrolase, carbohydrate, glucuronidase, gh79, heparan sulfate
Biological source	Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161)
Total number of polymer chains	1
Total formula weight	50814.56
Authors	Armstrong, Z.,Wu, L.,Davies, G.J. (deposition date: 2021-09-23, release date: 2022-08-03, Last modification date: 2024-01-31)
Primary citation	de Boer, C.,Armstrong, Z.,Lit, V.A.J.,Barash, U.,Ruijgrok, G.,Boyango, I.,Weitzenberg, M.M.,Schroder, S.P.,Sarris, A.J.C.,Meeuwenoord, N.J.,Bule, P.,Kayal, Y.,Ilan, N.,Codee, J.D.C.,Vlodavsky, I.,Overkleeft, H.S.,Davies, G.J.,Wu, L. Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo. Proc.Natl.Acad.Sci.USA, 119:e2203167119-e2203167119, 2022 Cited by PubMed: 35881786 DOI: 10.1073/pnas.2203167119 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.24 Å)

Structure validation