7PSA

The acetogenin-bound complex I of Mus musculus resolved to 3.4 angstroms

This is a non-PDB format compatible entry.

Summary for 7PSA

• Entry DOI: 10.2210/pdb7psa/pdb
• EMDB information: 13611
• Descriptor: NADH-ubiquinone oxidoreductase chain 3, NADH-ubiquinone oxidoreductase chain 6, NADH-ubiquinone oxidoreductase chain 4L, ... (55 entities in total)
• Functional Keywords: inhibitor-bound, detergent-solubilised, nadh:ubiquinone oxidoreductase, membrane protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 45
• Total formula weight: 1072891.76

Authors

Grba, D.,Hirst, J. (deposition date: 2021-09-22, release date: 2022-04-06)

• Primary citation: Grba, D.N.,Blaza, J.N.,Bridges, H.R.,Agip, A.A.,Yin, Z.,Murai, M.,Miyoshi, H.,Hirst, J.; Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I.; J.Biol.Chem., 298:101602-101602, 2022; PubMed: 35063503; DOI: 10.1016/j.jbc.2022.101602

Experimental method

ELECTRON MICROSCOPY (3.4 Å)