7PS6

Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-44 and Beta-54 Fabs

Summary for 7PS6

• Entry DOI: 10.2210/pdb7ps6/pdb
• Related: 7PS5
• Descriptor: Beta-54 Fab heavy chain, CHLORIDE ION, Beta-54 Fab light chain, ... (11 entities in total)
• Functional Keywords: sars-cov-2 b.1.1.7 (alpha) variant, b.1.351 (beta) variant, p.1 (gamma) variant, b.1.617.2 (delta) variant, antibody, receptor-binding-domain, spike, neutralisation, viral protein/immune system, viral protein, immune system, viral protein-immune system complex
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 119224.42

Authors

Zhou, D.,Ren, J.,Stuart, D.I. (deposition date: 2021-09-22, release date: 2021-12-15, Last modification date: 2024-01-31)

• Primary citation: Liu, C.,Zhou, D.,Nutalai, R.,Duyvesteyn, H.M.E.,Tuekprakhon, A.,Ginn, H.M.,Dejnirattisai, W.,Supasa, P.,Mentzer, A.J.,Wang, B.,Case, J.B.,Zhao, Y.,Skelly, D.T.,Chen, R.E.,Johnson, S.A.,Ritter, T.G.,Mason, C.,Malik, T.,Temperton, N.,Paterson, N.G.,Williams, M.A.,Hall, D.R.,Clare, D.K.,Howe, A.,Goulder, P.J.R.,Fry, E.E.,Diamond, M.S.,Mongkolsapaya, J.,Ren, J.,Stuart, D.I.,Screaton, G.R.; The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.; Cell Host Microbe, 30:53-, 2022; PubMed: 34921776; DOI: 10.1016/j.chom.2021.11.013

Experimental method

X-RAY DIFFRACTION (2.26 Å)