7PQZ

Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with FI-3A and FD-11A Fabs

7PQZ の概要

• エントリーDOI: 10.2210/pdb7pqz/pdb
• 関連するPDBエントリー: 7PQY
• 分子名称: Spike protein S1, FI-3A Fab heavy chain, FI-3A Fab light chain, ... (7 entities in total)
• 機能のキーワード: sars-cov-2 antibody, receptor-binding-domain, rbd, spike, neutralisation, fi-3a, fd-11a, fd-5d, viral protein/immune system, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 118707.96

構造登録者

Zhou, D.,Ren, J.,Stuart, D.I. (登録日: 2021-09-20, 公開日: 2022-02-02, 最終更新日: 2024-01-31)

• 主引用文献: Huang, K.A.,Zhou, D.,Tan, T.K.,Chen, C.,Duyvesteyn, H.M.E.,Zhao, Y.,Ginn, H.M.,Qin, L.,Rijal, P.,Schimanski, L.,Donat, R.,Harding, A.,Gilbert-Jaramillo, J.,James, W.,Tree, J.A.,Buttigieg, K.,Carroll, M.,Charlton, S.,Lien, C.E.,Lin, M.Y.,Chen, C.P.,Cheng, S.H.,Chen, X.,Lin, T.Y.,Fry, E.E.,Ren, J.,Ma, C.,Townsend, A.R.,Stuart, D.I.; Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2.; Theranostics, 12:1-17, 2022; PubMed: 34987630; DOI: 10.7150/thno.65563

実験手法

X-RAY DIFFRACTION (3.2 Å)