7PQ3
Crystal Structure of the Ring Nuclease 0811 from Sulfolobus islandicus (Sis0811) in complex with its post-catalytic reaction product
This is a non-PDB format compatible entry.
Summary for 7PQ3
Entry DOI | 10.2210/pdb7pq3/pdb |
Related | 7PQ2 |
Descriptor | CRISPR-associated protein, APE2256 family, 3'-O-[(R)-{[(2S,3aS,4S,6S,6aS)-6-(6-amino-9H-purin-9-yl)-2-hydroxy-2-oxotetrahydro-2H-2lambda~5~-furo[3,4-d][1,3,2]dioxaphosphol-4-yl]methoxy}(hydroxy)phosphoryl]adenosine (2 entities in total) |
Functional Keywords | ring nuclease, crispr-associated protein, helix-turn-helix, antiviral protein, viral resistance, carf nucleotide-binding domain, crispr ring nuclease |
Biological source | Sulfolobus islandicus REY15A |
Total number of polymer chains | 2 |
Total formula weight | 64625.09 |
Authors | Molina, R.,Jensen, A.L.G.,Marchena-Hurtado, J.,Lopez-Mendez, B.,Stella, S.,Montoya, G. (deposition date: 2021-09-16, release date: 2021-11-24, Last modification date: 2024-01-31) |
Primary citation | Molina, R.,Jensen, A.L.G.,Marchena-Hurtado, J.,Lopez-Mendez, B.,Stella, S.,Montoya, G. Structural basis of cyclic oligoadenylate degradation by ancillary Type III CRISPR-Cas ring nucleases. Nucleic Acids Res., 49:12577-12590, 2021 Cited by PubMed: 34850143DOI: 10.1093/nar/gkab1130 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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