7PKI

Crystal structure of human ACE2 bound to the spike receptor-binding domain from a cave bat sarbecovirus closely related to SARS-CoV-2.

7PKI の概要

• エントリーDOI: 10.2210/pdb7pki/pdb
• 分子名称: Processed angiotensin-converting enzyme 2, GLYCEROL, BANAL 236 coronavirus spike receptor-binding domain, ... (11 entities in total)
• 機能のキーワード: coronavirus, receptor binding domain, human ace2., viral protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 94118.40

構造登録者

Baquero, E.,Rey, F.A. (登録日: 2021-08-25, 公開日: 2022-01-19, 最終更新日: 2024-02-07)

• 主引用文献: Temmam, S.,Vongphayloth, K.,Baquero, E.,Munier, S.,Bonomi, M.,Regnault, B.,Douangboubpha, B.,Karami, Y.,Chretien, D.,Sanamxay, D.,Xayaphet, V.,Paphaphanh, P.,Lacoste, V.,Somlor, S.,Lakeomany, K.,Phommavanh, N.,Perot, P.,Dehan, O.,Amara, F.,Donati, F.,Bigot, T.,Nilges, M.,Rey, F.A.,van der Werf, S.,Brey, P.T.,Eloit, M.; Bat coronaviruses related to SARS-CoV-2 and infectious for human cells.; Nature, 604:330-336, 2022; PubMed: 35172323; DOI: 10.1038/s41586-022-04532-4

実験手法

X-RAY DIFFRACTION (2.94234133444 Å)