7PJH
Crystal structure of the human spliceosomal maturation factor AAR2 bound to the RNAse H domain of PRPF8
Summary for 7PJH
| Entry DOI | 10.2210/pdb7pjh/pdb |
| Descriptor | Protein AAR2 homolog, Pre-mRNA-processing-splicing factor 8 (3 entities in total) |
| Functional Keywords | spliceosomal maturation, pre-mrna splicing, human aar2, human prpf8, splicing |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 75390.62 |
| Authors | Preussner, M.,Santos, K.,Heroven, A.C.,Alles, J.,Heyd, F.,Wahl, M.C.,Weber, G. (deposition date: 2021-08-24, release date: 2022-11-02, Last modification date: 2024-01-31) |
| Primary citation | Preussner, M.,Santos, K.F.,Alles, J.,Heroven, C.,Heyd, F.,Wahl, M.C.,Weber, G. Structural and functional investigation of the human snRNP assembly factor AAR2 in complex with the RNase H-like domain of PRPF8. Acta Crystallogr D Struct Biol, 78:1373-1383, 2022 Cited by PubMed: 36322420DOI: 10.1107/S2059798322009755 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
Download full validation report
