7PJF

Inhibiting parasite proliferation using a rationally designed anti-tubulin agent

7PJF の概要

• エントリーDOI: 10.2210/pdb7pjf/pdb
• 分子名称: Tubulin alpha-1B chain, Tubulin beta-3 chain, Designed ankyrin repeat protein (DARPIN) D1, ... (6 entities in total)
• 機能のキーワード: tubulin, microtubules, protozoa, apicomplexa, structural protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 118443.84

構造登録者

Sharma, A.,Gaillard, N.,Ehrhard, V.A.,Steinmetz, M.O. (登録日: 2021-08-24, 公開日: 2021-09-22, 最終更新日: 2024-01-31)

• 主引用文献: Gaillard, N.,Sharma, A.,Abbaali, I.,Liu, T.,Shilliday, F.,Cook, A.D.,Ehrhard, V.,Bangera, M.,Roberts, A.J.,Moores, C.A.,Morrissette, N.,Steinmetz, M.O.; Inhibiting parasite proliferation using a rationally designed anti-tubulin agent.; Embo Mol Med, 13:e13818-e13818, 2021; PubMed: 34661376; DOI: 10.15252/emmm.202013818

実験手法

X-RAY DIFFRACTION (1.862 Å)