7P8I

Receptor-binding domain (RBD) of the spike protein of the bat coronavirus RaTG13 virus in complex with the extracellular domain of human angiotensin-converting enzyme 2 (ACE2) - Crystal form 1

7P8I の概要

• エントリーDOI: 10.2210/pdb7p8i/pdb
• 分子名称: Processed angiotensin-converting enzyme 2, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: covid-19 bat coronavirus spillover zoonotic viral infection evolution, immune system, cell invasion
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 196260.67

構造登録者

Scietti, L.,Castelli, M.,Faravelli, S.,Clementi, N.,Mancini, N.,Forneris, F. (登録日: 2021-07-22, 公開日: 2022-08-03, 最終更新日: 2024-01-31)

• 主引用文献: Castelli, M.,Scietti, L.,Faravelli, S.,Clementi, N.,Forneris, F.,Mancini, N.; Evidence of SARS-CoV-2 Direct Evolution in R. affinis Bats Driven by Affinity and Dynamics Optimization of the Spike Protein; To Be Published,

実験手法

X-RAY DIFFRACTION (4.5 Å)