7P8F
Crystal structure of YTHDC1 with compound YLI_DC1_008
Summary for 7P8F
Entry DOI | 10.2210/pdb7p8f/pdb |
Descriptor | YTH domain-containing protein 1, ~{N},3-dimethyl-1~{H}-pyrazolo[4,3-d]pyrimidin-7-amine, SULFATE ION, ... (4 entities in total) |
Functional Keywords | ythdc1, inhibitor, complex, m6a, rna binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 42837.06 |
Authors | Bedi, R.K.,Li, Y.,Caflisch, A. (deposition date: 2021-07-21, release date: 2021-10-20, Last modification date: 2024-01-31) |
Primary citation | Li, Y.,Bedi, R.K.,Nai, F.,von Roten, V.,Dolbois, A.,Zalesak, F.,Nachawati, R.,Huang, D.,Caflisch, A. Structure-based design of ligands of the m6A-RNA reader YTHDC1 Eur J Med Chem Rep, 5:100057-, 2022 Cited by DOI: 10.1016/j.ejmcr.2022.100057PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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